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How UTIs Progress to Kidney Failure ⭕ Initial infection: UTIs usually start in the bladder or urethra. ⭕ Spread to kidneys: If untreated, bacteria can travel up the ureters into the kidneys, causing pyelonephritis (kidney infection). ⭕ Inflammation & damage: Repeated or severe kidney infections cause inflammation, tissue damage, and scarring. ⭕ Chronic impairment: Over time, scarring reduces kidney function, leading to chronic kidney disease (CKD). ⭕ Kidney failure: In severe cases, progressive
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