The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca 2+ ion channel found in neurons. [3][4] The NMDA …

Dec 11, 2022 · The N-methyl-D-aspartate (NMDA) receptor is a glutamate receptor, the human brain's primary excitatory neurotransmitter. It plays an integral role in synaptic plasticity, a …

Nov 18, 2025 · The N-methyl-D-aspartate (NMDA) receptor is a protein complex embedded in the membranes of brain cells, playing a fundamental role in communication between neurons.

Jul 19, 2025 · NMDA drugs are substances that interact with N-methyl-D-aspartate receptors in the brain, modifying the flow of information between nerve cells. This action influences a wide …

Nov 24, 2024 · NMDA receptors belong to the family of ionotropic glutamate receptors, distinct from G protein-coupled receptors (GPCRs). These receptors play a pivotal role in regulating …

Jan 7, 2026 · The synaptic plasticity mechanisms that are thought to underlie learning and memory require Ca2+ influx mediated by N-methyl-D-aspartate receptors (NM…

Here, we will review the relationship between NMDA receptor structure and function, the diversity and significance of NMDA receptor subtypes in the CNS, as well as principles and rules by …

NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the N -Methyl- D -aspartate receptor (NMDAR). They are commonly used as anesthetics for …

Aug 4, 2025 · Among these are NMDA receptors, embedded within the membranes of nerve cells. These receptors play a central role in how our brains process information and adapt to new …

Aug 2, 2023 · Since the discovery of N-methyl-D-aspartate ionotropic glutamate receptors (NMDARs) four decades ago, substantial efforts have been made to dissect their multifaceted …