May 30, 2017 · Marfan syndrome is one of the most common inherited disorders of connective tissue. It is an autosomal dominant condition occurring once in every 10,000 to 20,000 individuals.

Jan 23, 2023 · One of the most common inherited disorders affecting connective tissue, Marfan syndrome (MFS), is an autosomal dominant condition with a reported incidence of 1 in 3000 to 5000 …

This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. At least 25 percent of Marfan syndrome cases result …

From the perspective of having the genetic disorder, Marfan syndrome nearly always follows an autosomal dominant inheritance pattern: it only takes one non-working allele to cause the condition. …

Marfan syndrome is one of the most common inherited connective tissue conditions, with an estimated prevalence of approximately 1 in 5,000. It is an autosomal dominant condition resulting from disease …

Marfan syndrome is an autosomal dominant, highly penetrant, progressive genetic condition caused by pathogenic variants in the FBN1 gene encoding the glycoprotein fibrillin-1, which is the main …

Mar 11, 2024 · Marfan syndrome is an autosomal dominant condition. However, 25% of patients develop the disease due to de novo mutations, where the fibrillin gene mutates for the first time in the …

Jan 21, 2025 · Marfan syndrome is caused by changes (variants) in the fibrillin-1 (FBN1) gene. The condition follows an autosomal dominant inheritance pattern, meaning that only one copy of a FBN1 …

Oct 1, 2024 · One of the most common inherited disorders of connective tissue, Marfan syndrome (MFS, MIM #154700) is a predominantly autosomal dominant condition with a reported incidence of 1 in …

People affected by an autosomal dominant disease have a 50% chance of passing on the mutated gene to their biological child. Learn more about inheritance patterns from the National Library of Medicine …