Mammalian target of rapamycin (mTOR) is a kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. [5][6] It also promotes the …

Mammalian target of rapamycin (mTOR, now referred to as mechanistic target of rapamycin) is considered as the master regulator of cell growth.

Oct 2, 2023 · The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular metabolism, catabolism, immune responses, autophagy, survival, proliferation, and migration, to …

Nov 15, 2025 · The mechanistic target of rapamycin (mTOR), a serine/threonine kinase, serves as a central regulator of cellular growth, proliferation, metabolism, and survival through its two distinct …

Sep 28, 2017 · The mechanistic target of rapamycin, mTOR, is a downstream effector of many signaling pathways critical to human health. The 2017 Lasker Award for Basic Medical Research recognizes its...

The target of rapamycin (TOR) is a central regulator of growth, development, and stress adaptation in plants. This review delves into the molecular intricacies of TOR signaling, highlighting its …

Rapamycin engaged its intended biological target: autophagy. Treatment was associated with a 40–50% increase in circulating BECLIN-1 levels by days 60–90, alongside a more than two-fold reduction in …

Feb 26, 2024 · The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that functions via its discrete binding partners to form two multiprotein complexes, mTOR complex 1 and 2 …

mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of …

Jun 14, 2016 · Since the discovery that rapamycin, a small molecule inhibitor of the protein kinase mTOR (mechanistic target of rapamycin), can extend the lifespan of model organisms including …