The disappearance of "Today" show host Savannah Guthrie's mother three weeks ago has inspired volunteers to launch their own ...

Multiple police officers and SWAT officials were called to Pittsburgh's Oakland neighborhood, causing one road to be closed in the area Monday night.

Actor Robert Carradine has died, his family announced in a statement Monday night. He was 71.

A woman is facing charges after officials say she walked into a Pittsburgh Public Schools building and verbally threatened to harm two secretaries inside.

Two people were taken to the hospital following a multi-vehicle crash on I-79 in Washington County Monday night.

FEMA says it will focus only on immediate disaster responses until Congress restores Department of Homeland Security funding.

The U.S. military says it killed three people in a strike on an alleged drug-smuggling boat in the Caribbean Sea ...

Officials laid out a proposal to spur development of customized treatments for patients with hard-to-treat diseases, including for rare genetic conditions that the pharmaceutical industry has ...

The European Union has postponed a vote on a major trade deal with the U.S. amid uncertainty over new tariffs set to begin, prompting a warning from President Donald Trump.

President Donald Trump will deliver his first State of the Union address of his second term Tuesday night.

The program pairs newly diagnosed cancer patients with volunteer ambassadors who have successfully navigated their own cancer ...

The gold medal-winning U.S. Olympic women's hockey team has declined an invitation to President Donald Trump's State of the Union address, citing scheduling issues.