Mike Yastrzemski homered on the game’s first pitch, Michael Conforto also hit a solo shot and the San Francisco Giants beat the sinking Baltimore Orioles 5-3.

Michael Conforto had three hits, including a homer, and the San Francisco Giants frustrated the host Baltimore Orioles again, winning 5-3 on Wednesday night.

Anthony Santander hit a two-run home run in the bottom of the ninth Thursday, giving the Orioles a much-needed 5-3 win.