The Big Ten on CBS will feature a top-20 matchup in Week 4 as the No. 18 Michigan Wolverines host the No. 11 USC Trojans on Saturday for a 3:30 p.m. ET kickoff. The defending national champions were blown out at home by Texas but could get themselves back into the College Football Playoff mix with a run to the Big Ten Championship Game.

Cal leaves Tallahassee with its first ACC victory, and first win over the Seminoles in program history. While FSU will show improvement defensively, particularly along the defensive front, a returning Ott will power the Golden Bears to victory on the ground.

The college football schedule for Week 4 offers several major matchups. Our experts make picks for every Top 25 game, led by Oklahoma-Tennessee.