ahajournals.org6d
Abstract 4133122: Integrative Metabolomic Analysis of Triglyceride-Independent Lipoprotein Lipase Pathway Mechanisms for Coronary Artery Disease
Background: Strong genetic evidence supports the associations between key genes in triglyceride (TG) metabolism via the lipoprotein lipase (LPL) pathway (i.e., LPL, APOC3, and ANGPTL3) and coronary ...
Medscape1d
Prescription Omega-3 Fatty Acids and Their Lipid Effects: Physiologic Mechanisms of Action and Clinical Implications
Expert Rev Cardiovasc Ther. 2008;6(3):391-409. Phosphatidic acid phosphatase/phosphohydrolase (PAP) is an enzyme that catalyzes the conversion of phosphatidic acid to ...
pharmaphorum2d
How eligible patient numbers affect price of rare disease drugs in France
While the ATUc data confirmed efficacy on surrogate outcomes (HbA1c and triglyceride levels), it did not make up for lack of conclusive evidence regarding impact on mortality. The lack of value ...
Medscape3d
Treatment of Homozygous Familial Hypercholesterolemia
Clin Lipidology. 2014;9(1):101-118. TAUSSIG: a multicenter, open-label study to assess the long-term safety, tolerability, and efficacy of AMG145 on LDL-C in subjects with severe familial ...
verywellhealth5d
10 Causes of High Triglycerides in Diabetes
It's common to have high triglyceride levels if you have type 2 diabetes. When they are above the normal range, your provider might tell you that your triglyceride levels are elevated. Up to 70% of ...