Nature

Open-source protein structure AI aims to match AlphaFold

The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model.
C&EN

Conformational Analysis of Helical Peptides Incorporating Azepane-Based β-Amino Acids Prepared by an Ultrasound-Assisted Method

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.joc.5c01530. Most electronic Supporting Information files are available ...
Frontiers

MAPPs assays for non-clinical immunogenicity risk assessment: best practices recommended by the European immunogenicity platform

The use of the MAPPs (Major histocompatibility complex Associated Peptide Proteomics) assay by pharmaceutical companies, service providers, and academic laboratories is rapidly increasing, attesting ...
Frontiers

Development of potent HLA-A02:01-restricted peptide-based cytotoxic T-cells against SARS-CoV-2 infections in patients awaiting a kidney transplant

Background: Controlling viral infections prior to solid organ transplantation is vital for successful engraftment and overall well-being of patients. One promising approach involves the deployment of ...
C&EN

Applicability Domain of Peroxidase Peptide Reactivity Assay (PPRA): Chemical Structure Analysis and Grouping of Peptide Depletion Patterns

Global Product Stewardship, The Procter & Gamble Company, 8700 Mason Montgomery Rd., Mason, Ohio 45040, United States ...