The body has to clear away dead cells and other unnecessary or unneeded stuff, and one mechanism that is crucial to the ...

Prior research on the potential role of cytokines found that IL-6 signaling can reprogram and alter T-cell immune responses ...

Across studies, the rate of sudden death in ibrutinib-treated patients ranged from 0.49 to 0.788 per 100 patient-years, roughly double that seen in comparators. In contrast, pooled analyses of ...

Novel nephron organoids that can be fine-tuned to represent the proximal convoluted tubule or loop of Henle have been ...

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

Taken together with previous observational, genomic, and early trial data, our findings support the integration of aspirin into clinical practice for a molecularly defined subgroup of patients with ...

ESMO 2025 showcased the breadth and urgency of breast cancer research, which remains one of the most diagnosed malignancies ...

Activation of the complement cascade of proteases has been linked to autoimmune and kidney diseases, including systemic lupus ...

Inventisbio Co. Ltd. and Inventisbio LLC have synthesized phosphatidylinositol 3-kinase α (PI3Kα) E542K mutant inhibitors reported to be useful for the treatment of cancer, PIK3CA-related overgrowth ...

Researchers at Zhejiang University and Zhongshan Institute for Drug Discovery have discovered phosphatidylinositol 3-kinase δ (PI3Kδ) and mammalian target of rapamycin (mTOR; FRAP1) dual inhibitors ...