Proton pump inhibitors are a class of medications used to treat conditions like GERD and ulcers. They work by blocking the ...

Taking Out OGA. The rationale behind small-molecule OGA inhibition is that these drugs will decrease tau hyperphosphorylation ...

The research also highlights potential avenues for repurposing existing drugs. Researchers found that trimethoprim and ...

Researchers reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected 'second jobs' within the nucleus, orchestrating critical ...

Metabolic enzymes, typically associated with energy production, are now discovered to also play essential roles in the nucleus, such as orchestrating cell division and DNA repair. This breakthrough, ...

Metabolic enzymes are moonlighting outside of their traditional neighbourhood ... The research on IMPDH2 also studied its interaction with PARP1, a protein already targeted by existing cancer drugs.

Ibuprofen counters problems caused by mutations in the MAN1B1 gene, fruit fly tests show. Early results in three children are ”fairly positive.” ...

Researchers have found a new way to use biocatalysis to improve the production of critical raw materials required for ...

Scientists have identified an enzyme that may play a crucial role in ... Future treatments could include drugs that block GSTO2, to halt or slow the progression of the disease.

Pill testing is set to be legalised in Victoria after new legislation was passed on Tuesday night. The state is the first to introduce new laws around pill testing and it’s come just in time ...

They found that a specific enzyme — a fatty acid amide hydrolase (FAAH) — from Faecalibacterium prausnitzii significantly influences immune function pathways through its role in hydrolyzing ...