GNPC: Mining 40,000 Fluid Samples for Neurodegeneration Markers . Add To My AlzForum; 27 Jun 2025. Assembled by the Global Neurodegeneration Proteomics Consortium, the dataset represents the largest ...

A documentary of country legend Glen Campbell's life and “Goodbye Tour” following his diagnosis of Alzheimer's ...

Missense mutations in LRRK2 were first identified as a cause of Parkinson’s disease (PD) in 2004. Subsequent studies showed that these mutations account for up to 10 percent of familial cases, with ...

Species: Mouse Genes: MAPT Mutations: MAPT P301L Modification: MAPT: Transgenic Disease Relevance: Alzheimer's Disease, Frontotemporal Dementia Strain Name: Thy1-hTau.P301L Genetic Background: FVB/N ...

Overview. Pathogenicity: Alzheimer's Disease : Pathogenic, Cerebral Amyloid Angiopathy, Down's Syndrome ACMG/AMP Pathogenicity Criteria: PS1, PS2, PS3, PS4, PM1 Clinical Phenotype Studied: Alzheimer's ...

Steven T. Proulx University of Bern; Li Xin Theodor Kocher Institute, Univeristy of Bern; Posted: 12 Jun 2025 It has long been acknowledged that CSF drains to the deep cervical lymph nodes (Bradbury ...

Zhongcong Xie The University of Texas Health Science Center at Houston; Guang Yang Columbia University; Posted: 04 Jun 2025 We were surprised to find that conditional knockout of PERK in astrocytes ...

05 Jun 2025. Sleep tight, don’t let the tangles bite! In the May 27 Nature Neuroscience, researchers led by David Holtzman at Washington University School of Medicine, St. Louis, report that the sleep ...

10 Jun 2025. Parkinson’s disease (PD) is the second most common neurodegenerative disorder, after Alzheimer’s. Clinicians often use the mnemonic TRAP to recall its four key motor symptoms: tremor, ...

On May 13 in Immunity, a collaboration of scientists in the labs of Kiavash Movahedi from the University of Brussels in Belgium, Chris Bennett at University of Pennsylvania, Philadelphia, and David ...

Present in Parenchyma. In double reporter mice, microglia-like macrophages derived from monocytes (red) co-exist with yolk sac-derived microglia (green).. Using single-cell transcriptome analysis, the ...

Annexin A6 belongs to a family of phospholipid-binding proteins that repair and remodel cell membranes (image below). Previously, Vassar and colleagues had found that A6 rapidly latches onto neuronal ...