gut.bmj1d
Effect of faecal occult blood screening on mortality from colorectal cancer: results from a randomised controlled trial
Background: Three large randomised trials have shown that screening for colorectal cancer using faecal occult blood (FOB) tests can reduce the mortality from this disease. Two national pilot studies ...
gut.bmj1d
Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis
Correspondence to: Dr M Prince, Centre for Liver Research, 4th Floor William Leech Building, Newcastle University Medical School, Framlington Place, Newcastle NE2 4HH, UK; Martin.prince{at}ncl.ac.uk ...
gut.bmj1d
Pathology of idiopathic megarectum and megacolon
Background—The aetiology and pathology of both idiopathic megarectum and idiopathic megacolon are unknown. In particular, it is unknown whether there are abnormalities involving enteric nerves or ...
gut.bmj2d
Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways
2 Microbiology and Tumour Biology Centre, Karolinska Institute, Stockholm, Sweden 3 Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden 4 Microbiology and Tumour ...
gut.bmj2d
PTH-28 Elemental formula and LOFFLEX nutrition therapy; an effective but neglected treatment strategy in Crohn’s disease
Introduction Nutrition therapy in treatment of Chron’s Disease (CD) is not adequately highlighted in adult guidelines despite strong evidence supporting its therapeutic efficacy and thus, this option ...
gut.bmj2d
P207 Effects of fluconazole, gemfibrozil, and rifampin on the pharmacokinetics, safety, and tolerability of etrasimod
Introduction Etrasimod (ETR), a once-daily (QD), oral, selective sphingosine 1-phosphate receptor modulator in clinical development for immune-mediated inflammatory disorders, is a substrate of ...
gut.bmj4d
Measurement of normal portal venous blood flow by Doppler ultrasound.
Department of Medical Physics, Bristol and Weston Health Authority. The volume flow rate of blood in the portal vein was measured using a duplex ultrasound system. The many errors inherent in the ...
gut.bmj4d
Pathophysiology of functional dyspepsia
Functional dyspepsia is a symptom complex characterised by postprandial upper abdominal discomfort or pain, early satiety, nausea, vomiting, abdominal distension, bloating, and anorexia in the absence ...
gut.bmj6d
Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome
Correspondence to Dr G Nicholas Verne, Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112-2699, USA; gverne{at}tulane.edu Background More effective treatments are ...
gut.bmj7d
Protective effect of metronidazole on uncoupling mitochondrial oxidative phosphorylation induced by NSAID: a new mechanism
a Department of Gastroenterology, University of São Paulo (USP) Medica1 School, São Paulo, Brazil, Laboratory of Medical Investigation (LIM 07), General Clinics Hospital of the USP Medical School, b ...
gut.bmj7d
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
gut.bmj8d
Intestinal reticulosis as a complication of idiopathic steatorrhoea
Three patients who had idiopathic steatorrhoea associated with reticulosarcoma of either the jejunum or the ileum are described. Previously reported cases with these features are reviewed and the ...