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Treating patients with lung cancer always calls for a focus on informed and shared decision-making, according to expert ...
Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was ...
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GlobalData on MSNASCO25: MSD’s KRAS G12C drug shows early promise in Phase IMSD’s investigational KRAS G12C inhibitor has shown signs of anti-tumour activity when used both alone and in combination ...
Colorectal cancer is one of the most common types of tumor and is responsible for around 10% of cancer-related deaths ...
In mice, engineered immune cells shrink pancreatic and other tumours bearing a mutant version of the KRAS protein.
DNA methylation, RTK pathway changes, and KRAS amplifications may drive resistance to sotorasib plus panitumumab in KRAS G12C ...
Both ERAS-4001 and potential best-in-class pan-RAS molecular glue ERAS-0015 received IND clearance in May ahead of company guidance. Initial Phase 1 monotherapy data for both RAS- ...
InxMed Co., Ltd, a clinical-stage biotechnological company, pioneering therapies to transform cancer treatment, released latest clinical data from a Phase Ib/II clinical trial (NCT06166836; ...
Lim, M.D., Erasca’s chairman, CEO, and co-founder. “ERAS-4001 targets multiple KRAS mutations as well as wildtype KRAS but spares HRAS and NRAS, potentially enabling a better therapeutic ...
The next-generation KRAS G12C inhibitor MK-1084 showed promising efficacy and safety as a single agent and in combinations for advanced colorectal cancer.
Durability follow-up data of the single-arm cohort in first-line KRAS G12C-mutant non-small cell lung cancer (NSCLC) patients, regardless of PD-L1 expression, who received ifebemtinib + garsorasib ...
Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was predictive of survival outcomes for patients with advanced KRAS G12C-mutated non ...
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