While glucose, or sugar, is a well-known fuel for the brain, Weill Cornell Medicine researchers have demonstrated that ...

A groundbreaking study reveals that neurons can burn fat, challenging the long-held belief that the brain relies solely on glucose for fuel.

In a groundbreaking study, researchers at Weill Cornell Medicine have discovered that the brain can tap into fat droplets as ...

Familial chylomicronemia syndrome is a rare genetic disorder characterized by reduced or absent lipoprotein lipase (LPL) activity. 1-4 LPL mediates lipolysis of plasma triglycerides in ...

Triglycerides can be broken down through a reaction involving the pancreatic lipase enzyme responsible for hydrolyzing the ester bonds and allowing the fatty acids to be released from the glycerol ...

To uncover how the parasite induces fat loss, the researchers used wildtype and knockout mice that lacked adipocyte triglyceride lipase (ATGL), a key enzyme in lipolysis, in their adipose tissues.

APOC3 is a key regulator in triglyceride-rich lipoprotein metabolism while ANGPTL3 regulates lipids and lipoproteins, including the metabolism of triglycerides, by inhibiting lipoprotein lipase, ...

When triglyceride lipase is silenced, the glyceride levels in midguts and fat bodies tend to increase, while there was a large drop in glyceride levels in ovaries by the end of 24 hours.

PASADENA, Calif., May 29, 2024--Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced results from the Phase 2b double blind, randomized ARCHES-2 study of investigational zodasiran ...