Protein linked to airway obstruction in asthma provides a potential treatment target
Researchers at National Jewish Health and colleagues have identified a mechanism involved in the formation of mucus plugs in ...
eLife21h
Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis
Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease. Current efforts to ...
Frontiers21d
Retraction: Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia
Zhu Y, Chen Y, Xie D, Xia D, Kuang H, Guo X and Ning B (2023) Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia. Front. Immunol. 14:1260584 ...
Medscape28d
Th-17 Cells in the Lungs?
Stefan Ivanov, Lung Immunology ... of activated CD4 cells. IL-17 contributes to the accumulation of neutrophils and, under certain conditions, to the accumulation of macrophages in the ...
Medscape28d
C-reactive Protein at the Interface Between Innate Immunity and Inflammation
FcγR on the surface of macrophages, DCs or PMNs. The type of FcγR involved helps to determine the downstream effect of this binding. CRP: C-reactive protein; DC: Dendritic cell; FcγR ...
Frontiers29d
Allergenic protein-induced type I hypersensitivity models: a review
This review summarizes various methods used to establish animal models of common allergenic protein-induced type I hypersensitivity and IgE-mediated cell models and discusses their advantages and ...
BioWorld29d
Lung macrophages put invasive breast cancer cells to sleep
Now, scientists have shown in a study published Oct. 7, 2024, in Cell, that the limiting of disseminated breast cancer cells (DCCs) to metastasize in the lungs is due to alveolar macrophages, which ...