Researchers have identified a potential treatment for Sandhoff and Tay-Sachs diseases -- two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain and ...

Heightened levels of stress can trigger HAE attacks, which further contribute to decreased quality of life. A review of 48 studies found that among other factors, HAE attack frequency, ...

Then, cholesteryl esters (CEs), the main form of cholesterol in lipoproteins, are hydrolyzed to free cholesterol (FC) at an acidic pH by lysosomal acid lipase (LAL), encoded by the LIPA (lipase A) ...

Lauric acid is a saturated fatty acid found in vegetable fats, primarily coconut, coconut milk, and coconut oil. The plant compound is not found alone in nature and can only be extracted from the ...

Boric acid suppositories are a cost-effective alternative treatment method that may be used to treat vaginal infections, such as yeast infections or bacterial vaginosis. They may be prescribed by your ...

(L-R) Jim Palma, executive director, TargetCancer Foundation; Jenifer Waldrop, MS, executive director, Rare Disease Diversity Coalition; and Edward Neilan, MD, PhD, chief medical and scientific ...

is a fatal genetic muscle disorder caused by a deficiency of acid α-glucosidase (GAA). 1 This enzyme defect results in lysosomal glycogen accumulation in multiple tissues, with cardiac and ...

A 14-year-old schoolgirl has been seriously injured after a substance, believed to be acidic, was thrown at her and another teenager outside her school in west London, with a staff member also ...

Please verify your email address. Players need lots of Acid to craft Tier 3 Aluminum in Once Human, obtainable from Stardust-corrupted enemies, especially Jellyfish. Several Acid farming locations ...

Lysosomal acidification is a key feature of healthy cells. Inability to maintain lysosomal acidic pH is associated with aging and neurodegenerative diseases. However, the mechanisms elicited by ...