Inhibition of LKKR2 may rescue neurons that are dying due to a type of Parkinson’s disease that is caused by a single genetic mutation.

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

Locust plagues pose a significant threat to global agriculture, economies and the environment. Current control methods rely ...

A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia ...

The efficacy of camptothecin-based topoisomerase I (Topo1) inhibitors, which are widely used as anticancer therapies, is often limited by resistance mechanisms, primarily involving mutations in the ...

A team of zoologists, molecular engineers and pest control specialists at the Chinese Academy of Sciences, working with a ...

Researchers at the University of Illinois Urbana-Champaign have discovered important new clues in the mystery of how an ...

A study published in the March 29 issue of Aging (Aging-US) suggests that certain senolytic compounds can inhibit specific forms of brain enzymes associated with Alzheimer’s disease (AD) without ...

But it also shows how even a simple enzyme may have an extremely complex mechanism—and one that's hard to tackle, even with the latest AI tools. Ending esters ...