Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium ...

The research also highlights potential avenues for repurposing existing drugs. Researchers found that trimethoprim and ...

This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...

Drugmaker HLB will acquire a controlling stake in Genofocus, Korea’s top domestic enzyme producer, as part of the ...

Isoniazid is a first-line medicine for tuberculosis (TB) treatment. It is a prodrug activated by the mycobacterial catalase-peroxidase enzyme KatG. However, the development of isoniazid resistance ...

Staphylococci were identified by colony morphology, Gram stain, catalase reaction, bacitracin susceptibility and coagulase tube test. The S. aureus ATCC 25923 strain was used as positive control in ...

However, whether T. chebula might serve as a safe, effective treatment for mild cognitive impairment (MCI) has not been sufficiently studied. As an early step, a research team has conducted a ...

Acute kidney injury (AKI) is a rapid deterioration in kidney function that occurs within 48 hours of an initiating event and is associated with an absolute increase in serum creatinine of ≥26.4 ...