The management of alcoholic pancreatitis is mostly reactive ... are believed to include premature intracellular activation of digestive enzymes, which leads to autodigestion.

This study provides convincing evidence for functional subpopulations of β-cells responsible for Ca2+ signal initiation and maintenance using novel three-dimensional light sheet microscopy imaging and ...

Nammi Therapeutics, Inc. (Nammi), a clinical stage immuno-oncology company with a diverse pipeline created with the Masked-Immunocytokine (MIC) and Nammisome platforms, announces dosing of the first ...

Good afternoon, everyone. Thank you for standing by. Welcome to CytomX Therapeutics third quarter, 2024 Financial results call. Please be advised that today's call is being recorded. I would now like ...

In our view, chronic pancreatitis requires three “hits”, which can include environmental stressors, pancreatic injury from trypsinogen activation ... pathways of zymogen/activated digestive enzyme ...

Mechanistically, key metabolic enzymes involved in gemcitabine ... dFdCMP to dFdUMP preventing further activation of dFdCMP to dFdCTP. To the best of our knowledge, differential expression of Nt5cAs ...

The authors analyze a comprehensive cohort of human plasma samples to identify an extracellular vesicles protein signature for early diagnosis of pancreatic cancer ... 0043299), myeloid leukocyte ...

Novel method identified protein degraders that target Pin1, a protein involved in pancreatic cancer development.

A new drug strategy that regulates the tumor immune microenvironment may transform a tumor that resists immunotherapy into a susceptible one, according to a new study.

A new drug strategy that regulates the tumor immune microenvironment may transform a tumor that resists immunotherapy into a ...