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eLife
1d
Biochemical and structural insights into the auto-inhibited state of Mical1 and its activation by Rab8
The compelling evidence explains how Rab8 family members bind at two sites to allosterically regulate MICAL1, and relieve an auto-inhibited state unable to bind actin. This study lays the basis for ...
GEN
5d
Discovery of Nuclear Roles for Metabolic Enzymes Could Lead to New Anticancer Strategies
Studies suggest the cell is more interconnected than previously thought, opening up "exciting possibilities for science and medicine." ...
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