General Motors swung to a loss in the fourth quarter on huge charges related to China, but still topped profit and revenue expectations on Wall Street.

Grant reviews have been suspended at the NIH. This could be an omen.

Activist investor Ancora Holdings has built a stake in US Steel and wants the steelmaker to drop its merger agreement.

Aaron Zitner is a reporter and editor in The Wall Street Journal's Washington bureau ... Globe and the Concord (N.H.) Monitor. Raised in Pittsburgh, he is a graduate of Oberlin College.

Knowles would join James Franklin's Penn State staff after three seasons at Ohio State, where he won a national championship.

Unlike past years, when the Bills’ passing playbook depended on deep downfield looks, this current receiving corps has plenty of big capable pass catchers for quick short shots that then grind out yards after the catch (third highest YAC/completion). It’s an ideal foil to the Chiefs’ aggressiveness.

Logan's prediction: Buffalo running back James Cook has seen his production rise lately and should be front-and-center in the Bills' attack as they look to dethrone the Chiefs. The rivalry between the Buffalo Bills and Kansas City Chiefs has been one-sided so far, with Kansas City beating Buffalo in three straight postseason meetings.

A Norfolk Southern train derailment in East Palestine, Ohio, spilled chemicals, sickening residents. Now researchers are tracking the long-term health effects.

There are so many hidden gems and unique things to do in Pittsburgh, Pennsylvania. Learn more about the quirky, cool and cultured places to visit.

The weak pace of loan growth is a worry, particularly for regional lenders.

Downtown Pittsburgh is undergoing an ambitious public-private effort to reinvigorate a lagging city corridor. Is this a lesson for Market East?

S&P 500 futures are up 0.5%. Dow Jones Industrial Average futures are gaining 0.4%. Nasdaq 100 futures are rising 0.7%. On Wednesday, the Dow Jones Industrial Average fell 137 points, or 0.31%, to 44,