Mitochondrial diseases, arising from mutations in mitochondrial DNA (mtDNA), are a diverse group of disorders that lead to ...

In human cells, lipid droplets (LDs) predominantly contain either cholesteryl esters or triacylglycerols. This article ...

In Davidi et al , we performed a high-throughput spectrophotometric assay on over 100 rubiscos. The kinetic parameters of the ...

How cardiac cell fates are specified during heart development remains elusive. This study identifies a level-dependent role ...

Multi-epitope immunopurifications of huntingtin (HTT) from vulnerable brain regions of Huntington’s disease (HD) models ...

Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...

WFS1 and CISD2 regulate IP3R activity through their interaction. In Wolfram syndrome, their dysfunction reduces cytosolic ...

Inflammatory arthritis encompasses a group of autoimmune diseases, including rheumatoid arthritis (RA), psoriatic arthritis ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Immune memory plays a critical role in the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Genomics has transformed the diagnostic ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Saccharin has been part of the human diet for ...