Rationale Higher blood pressure variability (BPV) has been associated with adverse cardiovascular events in various clinical ...

Background Cardiovascular disease (CVD) and light chain (AL) amyloidosis are important causes of morbidity and mortality in patients with multiple myeloma (MM). Additionally, MM therapies can have ...

For some time the alcohol-heart relationship has been a controversial topic in heart disease epidemiology.1–3 The relationship between average alcohol consumption and ischaemic heart disease (IHD) is ...

Background Chronic total occlusion (CTO) often triggers collateral coronary development, yet the relationship between angiographically graded collaterals and myocardial viability remains incompletely ...

Objective Exercise intolerance is a clinical hallmark of chronic conditions. The present study determined pathophysiological mechanisms of exercise intolerance in cardiovascular, neuromuscular, and ...

Objectives To investigate whether preoperative echocardiographic evaluation of ventricular function, especially right ventricular systolic and diastolic parameters including speckle-tracking analysis, ...

Objective To determine provision of MRI for patients with cardiac implantable electronic devices (CIEDs; pacemakers and defibrillators) in England, to understand regional variation and assess the ...

Introduction The clinical management of Obstructive Hypertrophic Cardiomyopathy remains challenging, and the phase III EXPLORER-HCM trial has demonstrated that the novel cardiac myosin inhibitor ...

Objectives Patients’ backgrounds and clinical outcomes in urgent/emergent/salvage transcatheter aortic valve replacement (Em-TAVR) remain unclear. We investigated patient characteristics and the ...

Background Heterogeneous myocardial contraction is common in myocardial disease and linked to ventricular arrhythmias, but its frequency and relevance in the general population remain unclear. This ...

Objectives Relationship between atrial fibrillation (AF) and inflammation was shown in previous studies. However, there was limited data about the association between the periodontitis and AF in the ...

Background The expansion of universal health coverage (UHC) in many low- and middle-income countries (LMICs) has occurred alongside a growing burden of chronic disease and multimorbidity. Heart ...