Delivering a CRISPR-Cas-derived adenine base editor as a short-lived protein-guide RNA complex enabled efficient PCSK9 ...

The US FDA has accepted Intellia Therapeutics’ application for lonvoguran ziclumeran (lonvo-z, formerly NTLA-2002) and ...

Delivering CRISPR-Cas9 as mRNA in lipid nanoparticles preserved the fitness and erythroid potential of edited human ...

A gene-edited pig kidney kept a patient with end-stage kidney disease dialysis-free for 271 days, then failed and was removed without leaving the recipient sensitised against human donors. Eighty-two ...

CMN Intelligence has released the CMN Clinical Trials Q2 2026 Global Report, based on data from the CRISPR Medicine News Global Clinical Trials... Copenhagen-based SNIPR reports today that an ...

Precision BioSciences reported progress with its CRISPR-Cas–based ARCUS gene editing therapy PBGENE-DMD, designed to excise dystrophin exons 45–55 and restore near full-length dystrophin expression.

Researchers have used a novel CRISPR-Cas library to identify essential microRNAs in prostate cancer cells, revealing miR-483-3p as a key regulator of cell survival. The study found that disrupting ...

In vivo genome editing is entering an important new phase. Advances in editing technologies, delivery platforms and translational science are bringing the prospect of one-time, directly administered ...

The Federation of American Societies for Experimental Biology (FASEB) conference on Genome Engineering kicks off one month from now in Rome, Italy. The Federation of American Societies for ...

Intellia Therapeutics has reported positive three-year follow-data from the ongoing Phase 1/2 trial of lonvo-z (formerly known as NTLA-2002) in patients with hereditary angioedema. The data show that ...

To get more CRISPR Medicine News delivered to your inbox, sign up to the free weekly CMN Newsletter here. Delivering a CRISPR-Cas-derived adenine base editor as a short-lived protein-guide RNA complex ...

Genome-wide CRISPR-Cas9 screens identified hundreds of genes that support or restrict cGAS–STING-induced type I interferon expression in human monocytic cells. The resulting map links interferon ...