This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

For cancer- and infection-fighting T cells, glucose offers far more than a simple sugar rush. A new discovery by Van Andel Institute scientists reveals that glucose, an essential cellular fuel that ...

Glucose is more than just an essential fuel for T cells — significant amounts of glucose also are used to build large molecules called glycosphingolipids (GSLs). These sugar-fat compounds are ...

Our body is made up of millions of cells that coordinate daily function. They are constantly working to maintain activity and keep us healthy. Cells activate, proliferate, and conduct specialized ...

Short-term nutritional state can reshape T cell metabolism, with post-meal lipid metabolism enhancing T cell metabolic ...

T cells are crucial components of our immune system, serving as critical protectors against infection and disease. But there ...

For cancer- and infection-fighting T cells, glucose offers far more than a simple sugar rush. Subscribe to our newsletter for the latest sci-tech news updates. A new discovery by Van Andel Institute ...