An isoform of HMGB1, ReHMGB1, both drives cellular senescence and is secreted by senescent cells. The molecular pathway that ReHMGB1 uses to cause these changes has been identified. Interfering with ...

The LRI Summer Scholars Program offers undergraduate students the opportunity to conduct biomedical research to combat diseases of aging, such as cancer, Alzheimer’s, and Parkinson’s Disease. Under ...

The FDA views aging as an inevitability, not a medical target. However, with Life Biosciences moving the first cellular reprogramming therapy into human trials this year, things might be changing ...

How did the year 2025 turn out for longevity biotech? Was it surprising or more of the same? Exciting or disappointing? Was the progress fast-moving or excruciatingly slow? What should we expect in ...

Life Biosciences is engaging in a clinical trial against two age-related eye diseases. This approach uses partial cellular reprogramming, which has never before been tried in humans. Life Biosciences ...

Using a gene therapy to cause the muscles of mice to produce FGF21 improved heart, liver, kidney, and brain function. This treatment prevented fibrosis and improved mitochondrial performance in these ...

How long can people live? This is not just a foundational question in science. The answer has important public policy implications and is of interest to us all. Recent scientific evidence has revealed ...

The 2025 Longevity Summit Dublin was held in July, and we have the highlights from the event for you along with the latest research updates and news from the conference. The Summit was founded by ...

Traditional and folk medicines offer many botanical extracts that can be tested by modern science for their medicinal properties and influences on aging. One such plant is the Bolivian prawn sage ...

Organized by representatives of major research institutions, Cold Spring Harbor Laboratory’s 13th Mechanisms of Aging meeting has invited multiple speakers from both industry and research, including ...

The LRI Post-Baccalaureate Fellowship Program, structured like an advanced internship, not only allows participants to work alongside our scientists with a degree of independence, but also promotes ...

7,000 steps a day seems to be sufficient for most health benefits of walking. Some conditions showed only small improvements with step counts beyond 7,000. Other conditions were more greatly improved ...