Huntington’s disease (HD) is caused by an expansion of a short DNA sequence — the letters C-A-G — located in the very first ...
In people with premanifest HD, lower scores on the visual thinking tests were linked with more movement changes over time.
A new Phase 1 study is testing SRP-1005, a huntingtin-lowering therapy given by injection under the skin. It’s early days, but this approach could add an important new arrow to the HD drug development ...
Spark and Roche issued a joint community letter to share that the first patient has been dosed in a new HD gene therapy trial. To capture your interest with a romance, let’s talk about how these ...
In plain language. Written by scientists. Two individuals with the same CAG repeat count can have vastly different HD journeys. A new study looking at individuals with 36-42 repeats shows that DNA ...
This week, HDBuzz is attending the HD2026 Milton Wexler Biennial Symposium in Boston, Massachusetts. Held every other year and organized by the Huntington’s Disease Foundation (HDF), this conference ...
On 25th June 2024, Wave Life Sciences shared the results of their SELECT-HD clinical trialclinical trial Very carefully planned experiments designed to answer specific questions about how a drug ...
People who develop Huntington’s disease (HD) are born with the genetic change that causes the disease. So why does it take decades, usually around 40 to 50 years, for the symptoms of the disease to ...
A group of researchers at the University of Pennsylvania, USA, has recently carried out an investigation to explore whether using a type of talking therapy, called Acceptance and Commitment Therapy ...
A new study shows that lowering MSH3, a key DNA repair protein, with antisense oligonucleotide (ASO) therapy can stop CAG repeat expansions in HD patient-derived brain cells. This could be a promising ...
August has been a packed month for Huntington’s disease (HD) research. We’ve looked at what can be learned from disappointing ...
Greetings from Day 2 of the CHDI HD Therapeuticstherapeutics treatments Conference! HDBuzz continues to provide summaries of the exciting talks from HD scientists gathered in Palm Springs from around ...
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