Author: Nita V Bhatt, FAPA, MD, MPH; Chief Editor: David Bienenfeld, MD more ...

Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2022. Szuhany KL, Simon NM ...

Generalized anxiety disorder (GAD) is characterized by excessive and persistent anxiety and worry about multiple events or activities that is difficult to control. The anxiety and worry occur more ...

The etiology of bullous disease of diabetes is unknown. Prominent acral accentuation of the disease's lesions suggests a susceptibility to microtrauma-induced changes. However, most patients develop ...

The osmotic fragility test (OFT) is used to measure erythrocyte resistance to hemolysis while being exposed to varying levels of dilution of a saline solution. There is no true consensus among ...

Nontreponemal tests typically become positive about 2 weeks after infection and revert to nonreactive following adequate treatment. They are positive in nearly all patients with primary and secondary ...

The following organizations have released guidelines for the management of thyroid disease. Key diagnostic and treatment recommendations have been reviewed and integrated throughout the article.

Without treatment, tropical sprue runs a relapsing course and can result in severe malnutrition. Treatment involves antibiotic therapy and replacement of nutrient deficiencies (eg, folic acid, vitamin ...

Speckled lentiginous nevus (also referred to as nevus spilus) is a patch of hyperpigmentation that can be seen on any area of the body. This patch contains a variable number of darkly pigmented ...

The normal reference value for the activated protein C resistance (APCR) ratio is greater than 2.0. [1] A falsely low APCR ratio (< 2.0) may be seen in those with conditions with reduced protein S ...

Povidone-iodine 1.25% ophthalmic solution may be as effective as topical antibiotics, especially in resource-limited settings There is no data supporting the cost-effectiveness of antibiotics for mild ...

The following organizations have released guidelines for the management of psychogenic nonepileptic seizures (PNES). Key diagnostic and treatment recommendations have been reviewed and integrated ...