The announcement Sunday that former President Joe Biden was diagnosed with advanced prostate cancer has some people wondering how the disease could have been missed.

The revelation of former President Joe Biden’s cancer diagnosis has seemed to halt the ongoing debate over his fitness for office. But the co-author of the new book “Original Sin” tells Variety that conversation is fair,

The test can catch cancer early, but it can also lead to false alarms or find slow-growing tumors that wouldn’t cause problems, especially in older men.

House Republicans want to hear from former President Joe Biden’s doctor and four key aides to discuss his mental and physical decline — after the ex-president, 82, revealed Sunday that he has prostate cancer ahead of the Tuesday release of a bombshell book on the concealment of his waning mental faculties as he sought re-election last year.

Former President Joe Biden has been diagnosed with an "aggressive form" of prostate cancer that has spread to his bones, his office said in a statement on Sunday.

Former President Joseph R. Biden Jr.’s office pushed back on speculation that there had been a coverup around the illness.

The former President and his family “are reviewing treatment options with his physicians,” Biden’s office said.