This Review focuses on the pathways that catabolize cellular triacylglycerol ('fat'), namely, neutral lipolysis, acid lipolysis and lipophagy. Neutral lipolysis of triglycerides in cytosolic lipid ...

In a Phase III clinical trial, the drug volanesorsen significantly reduced blood fat (triglyceride) levels in participants with a rare disease called familial chylomicronemia syndrome; finding could ...

Please provide your email address to receive an email when new articles are posted on . The two main triglyceride-containing lipoproteins are very-low density lipoprotein (VLDL) and chylomicrons. VLDL ...

During infancy, the basic conditions for digestion of dietary fat differ from later in life. The bile salt–stimulated lipase (BSSL) is an enzyme expressed in the exocrine pancreas and in some species ...

People with familial chylomicronemia syndrome are born with a genetic mutation that means they can't produce an enzyme called lipoprotein lipase. Without the enzyme, their bodies can't break down ...

Familial hyperchylomicronemia syndrome (FCS) is a rare disorder you get from genes passed down from your parents. When you have it, your body isn’t able to break down (metabolize) fat. Specifically, ...

Please provide your email address to receive an email when new articles are posted on . Plozasiran lowered triglycerides and reduced risk for pancreatitis vs. placebo in patients with chylomicronemia.

PASADENA, Calif.--(BUSINESS WIRE)--Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced results from the Phase 2b double blind, randomized ARCHES-2 study of investigational zodasiran ...

The incidence of pancreatitis ranges from 1 in 1,066 live births [30] to 1 in 3,333 pregnancies. [31] The most common predisposing cause of pancreatic symptoms during pregnancy is cholelithiasis (i.e.

On the surface, this looked like an unusual case of heart attack. This 40-year-old patient of mine had a very desirable LDL ...