New organ-on-a-chip model of human synovium could accelerate development of treatments for arthritis
The synovium is a membrane-like structure that lines the knee joint and helps to keep the joint happy and healthy, mainly by producing and maintaining synovial fluid. Inflammation of this tissue is ...
Your synovium, or synovial membrane, is a thin membrane that lines the inside of joints like your elbow, knee, and shoulder. If you have psoriatic arthritis (PsA), this membrane may get thick and ...
Gene expression profiling distinguishes the compartments of psoriatic arthritis (PsA) at the molecular level, according to a study published online December 15 in Arthritis & Rheumatology. Up to 30% ...
The primary pathologic basis of rheumatoid arthritis resides in the synovium, a thin membrane lining the joint capsule. This membrane expands massively with the infiltration of immune and inflammatory ...
Synovectomy is surgery to remove part or all of the synovium, a layer of connective tissue that lines the inside of your joints. The synovium releases fluid and nutrients to keep your joints healthy ...
Rheumatoid arthritis (RA) is a complex and destructive inflammatory disease. Despite recent impressive advances in disease-modifying antirheumatic drugs and biologic therapies, treatment is not always ...
Synovial specimens from 24 patients with rheumatoid arthritis and eight patients with noninflammatory synovial conditions were studied for enzymatic activity capable of degrading collagen in vitro. On ...
Gene therapy presents a novel and effective way to extend delivery of important anabolic peptides like IGF-I to cells such as chondrocytes and synoviocytes. The goal is to transfer genes encoding ...
New organ-on-a-chip model of human synovium could accelerate development of treatments for arthritis
Researchers at Queen Mary University of London have developed a new organ-on-a-chip model of the human synovium, a membrane-like tissue that lines the joints. The model, published in the journal ...
New organ-on-a-chip model of human synovium could accelerate development of treatments for arthritis
In the UK, more than 10 million people live with a form of arthritis, which affects the joints and can cause pain, stiffness, and swelling. There is currently no cure for arthritis and the search for ...
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