The evaluation of new drugs designed to treat specific anemias should include a thorough understanding of underlying pathophysiology, with a focus on enhancing oxygen transport. In this concise review ...

Extract: This report presents the difference (Δ [H +)], and ratio (Δ p H), of the hydrogen ion activity between the inside and outside of the red cell for THAM-buffered and NaHCO 3-buffered ACD blood ...

Three patients heterozygous for hemoglobin Seattle were found to be anemic, with hematocrit levels of 24 to 33 per cent. Urinary erythropoietin excretion was 1 to 4 units per day. This low value ...