The big pharma company will no longer progress emugrobart to late-stage trials in FSHD and SMA due to a lack of efficacy.

In a letter to European patients, Roche said its decision to end development of “emugrobart” was based on the drug “not ...

The company discontinued developing emugrobart after two studies showed the drug didn’t achieve intended outcomes.

It's well known that spaceflight causes muscle atrophy and other biological changes in reduced gravity, and especially in ...

Skeletal muscle atrophy, or wasting, is a devastating and often irreversible syndrome during the aging process and for patients with advanced cancer. Muscle wasting involves a decrease in muscle mass ...

HOUSTON – A newly identified gene, atrogin-1, is involved in muscle loss associated with cancer, diabetes, fasting and kidney disease as well as in the atrophy occurring with disuse, inactivity, and ...

Cancer cachexia is a multifactorial syndrome marked by a severe loss of body weight due primarily to the wasting of skeletal muscle and adipose tissue. This syndrome is often accompanied by systemic ...

Muscle-on-chip systems are three-dimensional human muscle cell bundles cultured on collagen scaffolds. A Stanford University research team sent some of these systems to the International Space Station ...

Most of us have imagined how free it would feel to float around, like an astronaut, in conditions of reduced gravity. But have you ever considered what the effects of reduced gravity might have on ...

Muscles are made to move. Stretching and contraction stimulate biochemical pathways within muscle that maintain tissue health. When movement slows—when a broken limb is immobilized in a cast, for ...