Lithium—a decades-old treatment for bipolar disorder—may hold potential neuroprotective benefits beyond mood stabilization.

A once-daily dose of a medication, which averaged 195 mg, produced blood levels significantly lower than those typically ...

A pilot clinical trial has found that low-dose lithium tablets might help slow verbal decline among seniors with mild ...

A clinical trial suggests that low-dose lithium may slow the decline of verbal memory in older adults with mild cognitive impairment and amyloid-beta.

Glimmer of hope emerges in pilot trial of people with mild cognitive impairment ...

Researchers from the University of Adelaide are hopeful a recent biological discovery could lead to the precision treatment of bipolar disorder (BD). About 2.2% of the Australian population has a form ...

For many people who have bipolar I, lithium is that most elusive of pharmacological treatments, the “magic bullet”—a single intervention that completely eliminates the symptoms of a disease. Since the ...

A multicenter study of young patients with bipolar disorder provides what may be the most scientifically rigorous demonstration to date that lithium -- a drug used successfully for decades to treat ...

Changes Clinical Practice: Based on this large trial, lithium alone or a lithium-valproate combination should be used as first-line maintenance treatment for bipolar affective disorder type I instead ...

Lithium carbonate and valproate sodium are each recommended as monotherapy for preventing relapses in patients with bipolar disorder and are sometimes used in combination. However, combination therapy ...

Compared with lithium, valproate, olanzapine, quetiapine, and risperidone generally exhibited a lower likelihood of thyroid dysfunction. HealthDay News — Lithium is associated with an increased risk ...