Lipoprotein lipase (LPL) hydrolyzes circulating triglycerides (TGs). We previously showed that 3′-end haplotypes in the LPL gene influence atherosclerosis and insulin resistance. This study asked ...

Although able to hydrolyze a coconut-oil emulsion, the postheparin plasma of a patient with fat-induced (Type 5) hyperlipemia was unable to hydrolyze his own, normal human or rat chylomicrons.

During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the first patient to receive the ...

Over a 6-year period, patients with the genetic disease lipoprotein lipase deficiency (LPLD) who received a single gene therapy treatment of alipogene tiparvovec had a marked reduction in the severity ...

Purpose: Our aim was to test whether polymorphisms in the lipoprotein lipase (LPL) gene were associated with the progression of atherosclerosis in grafts examined in the Post-Coronary Artery Bypass ...

New Rochelle, NY, May 1, 2018--During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the ...

The European Commission approves the Western hemisphere’s first gene therapy, aimed at correcting a lipid-processing disorder. A series of rodent experiments showed that even with abundant food and ...