CARBONDALE, Ill. — Paxton DeLaurent threw four touchdown passes and Southeast Missouri State defeated Southern Illinois 38-21 on Saturday night.

The Giant City State Park Visitors Center is hosting an “Explore the Southern Illinois Outdoors” event in October ...

MOUNT VERNON, Ill. — A man from southern Illinois has won $1 million from a scratch-off lottery ticket. The Illinois Lottery ...

The winning ticket in the contest, which has a top prize of $10 million, was purchased at the Circle K at 1710 S. 10th St. in ...

The campus in deep southern Illinois is grappling with a nearly $9.5 million budget shortfall that its leader says is largely ...

After six suicide attempts, Southern Illinois native and former educator Jeffrey Morris has dedicated his life to teaching ...

The first witness called by those challenging the ban was a downstate gun dealer who testified AR-15-style guns are used for ...

METROPOLIS, Ill. -- A man was arrested after police say they saw him grab someone by the hair and punched in the mouth ...

Two Heartland projects from southern Illinois have been awarded an “Energizing Rural Communities Prize” from the U.S.

A Marion, Illinois, man appeared in U.S. District Court on Thursday to be sentenced on charges related to child sexual abuse ...

Southern Illinois says goodbye to Edward “Ike” Eigenrauch. Eigenrauch is most well known as the founder of the Ike Family ...

The bench trial for the challenge to Illinois’ gun and magazine ban continues in East St. Louis. Illinois enacted a ban on ...