Bone remodelling is a continuous adaptive process through which existing bone tissue is resorbed by osteoclasts and replaced by osteoblasts to maintain mechanical integrity and mineral homeostasis.

Millions of people worldwide suffer from osteoporosis, a disease marked by progressive bone loss, weakened skeletal strength and increased fracture risk. Healthy bone is maintained through continuous ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Throughout our lives, our bones are continuously remodeled to maintain strength, repair injuries and adapt to new stresses. Bone dynamics depend on two associated cell types: osteoblasts, which are ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan. Hypoxic conditions resulted ...