A new editorial paper titled "Targeting ABC transporters in PDAC—past, present, or future?" has been published in Oncotarget. In this new editorial, Cecilia Bergonzini, Elisa Giovannetti and Erik H.J.
“[...] it is crucial for the future application of ABC transporter inhibitors [...] to develop a stratification protocol [...] to identify those PDAC patients who ...
MDR3 defects are involved in the development of PFIC3, LPAC, ICP, and DILI. Sterolin 1/2 are cotransporters that transport plant sterols and can lead to sitosterolemia if mutated. MRP2 is responsible ...