Respiratory syncytial virus: from pathogenesis to potential …
WEBSep 27, 2021 · Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing respiratory tract infection in infants, the elderly and people with poor immune function, which causes a huge disease burden worldwide every year.
A new mechanism of respiratory syncytial virus entry inhibition …
WEBRespiratory syncytial virus (RSV) infection is a major cause of lower respiratory tract disease (LRTD) in young children and elderly individuals. In 2019, RSV was estimated to be responsible for more than 33 million episodes of acute LRTDs, 3.6 million hospitalizations, and 101,400 deaths among children under 5 years of age ( 1 ).
The Morphology and Assembly of Respiratory Syncytial Virus …
WEBAug 20, 2018 · Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract disease in young children. With repeat infections throughout life, it can also cause substantial disease in the elderly and in adults with compromised cardiac, pulmonary and immune systems.
Structural landscape of the respiratory syncytial virus ... - Nature
WEBSep 15, 2023 · Abstract. Human Respiratory Syncytial Virus (HRSV) is a prevalent cause of severe respiratory infections in children and the elderly. The helical HRSV nucleocapsid is a template for the viral...
The Morphology and Assembly of Respiratory Syncytial Virus
WEBAug 20, 2018 · Collectively, our results can facilitate the understanding of viral morphogenesis in RSV and other pleomorphic enveloped viruses. Keywords: cryo-electron microscopy (cryo-EM); cryo-electron tomography (cryo-ET); enveloped virus; human respiratory syncytial virus (RSV); viral morphogenesis; virus assembly.
Visualizing the replication of respiratory syncytial virus in cells …
WEBOct 3, 2014 · Respiratory syncytial virus (RSV) is the most important cause of severe lower-respiratory tract disease in calves and young children, yet no human vaccine nor efficient curative treatments...
Genetic diversity and molecular evolution of human respiratory ...
WEBJun 21, 2021 · Human respiratory syncytial viruses (RSVs) are classified into two major groups (A and B) based on antigenic differences in the G glycoprotein. To investigate circulating characteristics...
An Overview of Respiratory Syncytial Virus | PLOS Pathogens
WEBApr 24, 2014 · This article reviews the epidemiology, pathogenesis, and immunology of RSV, a leading cause of lower respiratory tract illness in infants and children. It also discusses the challenges and opportunities for RSV vaccine and therapeutic development.
The role of syncytia during viral infections - ScienceDirect
WEBSep 21, 2021 · Respiratory syncytial virus (RSV) is a common virus that causes infected lung and respiratory tract cells to fuse together resulting in multinucleated cells called syncytia (Saleh et al., 2020, Domachowske et al., 2000).
Respiratory Syncytial Virus: Infection, Detection, and New …
WEBRespiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children in North America and one of the leading causes of death of infants less than 1 year of age worldwide, second only to malaria.
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