Respiratory Syncytial Virus: Virology, Reverse Genetics, and ...
WEBHuman respiratory syncytial virus (RSV) is an enveloped, nonsegmented negative-strand RNA virus of family Paramyxoviridae. RSV is the most complex member of the family in terms of the number of genes and proteins. It is also relatively divergent and distinct from the prototype members of the family.
Respiratory syncytial virus - Wikipedia
WEBRespiratory syncytial virus (RSV), [a] also called human respiratory syncytial virus (hRSV) and human orthopneumovirus, is a contagious virus that causes infections of the respiratory tract. It is a negative-sense, single-stranded RNA virus. [2]
Respiratory syncytial virus: from pathogenesis to potential …
WEBSep 27, 2021 · In terms of structural morphology, RSV is a pleomorphic virus particle in which the filovirus is the dominant form, with a diameter of approximately 50 nm and a length from 1 to 10 μm, while the spherical virus particle is …
Structural landscape of the respiratory syncytial virus ... - Nature
WEBSep 15, 2023 · The authors explore the structural polymorphism of the Human Respiratory Syncytial Virus (HRSV) nucleocapsids, detect a non-canonical symmetry of the helical state resulting in variations in...
Structure and function of respiratory syncytial virus surface ...
WEBIn this chapter, we review the structure and function of the RSV surface glycoproteins, including recent X-ray crystallographic data of the F glycoprotein in its pre- and postfusion conformations, and discuss how this information informs …
Respiratory Syncytial Virus (RSV) - PMC - National Center for ...
WEBOct 31, 2014 · Simplified representation of the negative-sense RNA genome of respiratory syncytial virus (RSV) and the encoded proteins. The genome is shown 3′ with the leader extragenic region (ler) and with the 5′ trailer extragenic region (ter). The viral genes are depicted by the divided bars.
Respiratory syncytial virus entry and how to block it
WEBFeb 5, 2019 · The infectious cycle of respiratory syncytial virus (RSV) begins upon attachment of the virion to the apical surface of polarized, ciliated airway epithelial cells 95 (see the figure). The viral...
Genetic diversity and molecular evolution of human respiratory ...
WEBJun 21, 2021 · Human respiratory syncytial viruses (RSVs) are classified into two major groups (A and B) based on antigenic differences in the G glycoprotein. To investigate circulating characteristics and...
The Morphology and Assembly of Respiratory Syncytial Virus
WEBAug 20, 2018 · Recently, the three-dimensional (3D) structure of purified RSV particles has been elucidated, revealing three distinct morphological categories: spherical, asymmetric, and filamentous. However, the native 3D structure of RSV particles associated with or released from infected cells has yet to be investigated.
An Overview of Respiratory Syncytial Virus | PLOS Pathogens
WEBApr 24, 2014 · Respiratory Syncytial Virus (RSV) and Child Health. Respiratory Syncytial Virus (RSV), a member of the Paramyxoviridae family, is the leading cause of lower respiratory tract illness (LRI) in infants.
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