Respiratory Syncytial Virus: A Comprehensive Review of …
WEBMar 18, 2023 · Respiratory Syncytial Virus: A Comprehensive Review of Transmission, Pathophysiology, and Manifestation. With an increasing global incidence in children younger than the age of five, respiratory syncytial virus (RSV) is one of the most common viral respiratory infections worldwide.
Respiratory syncytial virus entry and how to block it | Nature Reviews ...
WEBFeb 5, 2019 · In this Review, we summarize the recent findings that have begun to elucidate RSV entry mechanisms, describe progress on the development of new interventions and conclude with a perspective on...
Respiratory syncytial virus infections in adults: a narrative review
WEBA systematic review found that, although oral ribavirin can decrease viral loads faster than supportive care alone in lower respiratory tract RSV infection, clinical benefits were only seen in haematological stem-cell transplant recipients and patients with haematological malignancy. 146 The dearth of therapeutic options has led to an increase ...
Update on current views and advances on RSV infection (Review)
WEBJun 15, 2020 · Respiratory syncytial virus (RSV) infection represents an excellent paradigm of precision medicine in modern paediatrics and several clinical trials are currently performed in the prevention and management of RSV infection.
Respiratory syncytial virus infection and novel interventions
WEBJul 12, 2023 · In this Review, we provide an overview of RSV interventions in clinical development, highlighting global disease burden, seasonality, pathogenesis, and host and viral factors related to RSV...
Respiratory syncytial virus: from pathogenesis to potential …
WEBSep 27, 2021 · In this review, we briefly describe the structure of RSV virions, the latest progress in understanding host surface virus-binding receptors and the viral life cycle. Then, we discuss recent advances in understanding the pathogenesis of RSV infection.
Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older ...
WEBApr 5, 2023 · Respiratory syncytial virus (RSV) infection causes considerable illness in older adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein–based (RSVpreF) vaccine...
The road to approved vaccines for respiratory syncytial virus
WEBSep 25, 2023 · In this review, I will discuss the impact of RSV on human health and how structure-based vaccine design set the stage for numerous RSV countermeasures to advance through late phase clinical ...
Severe respiratory syncytial virus infection in children: burden ...
WEBThe third paper focuses on RSV infections in adults and discusses diagnosis and disease burden, infection in vulnerable adult populations, prevention, and cost of care. 10 The fourth paper reviews the efficacy and safety of RSV vaccination and immunoprophylaxis in young children, explores potential regulatory, policy, and implementation ...
Respiratory syncytial virus prevention within reach: the vaccine and ...
WEBAug 8, 2022 · This review gives an overview of respiratory syncytial virus vaccines and monoclonal antibodies in clinical development highlighting different target populations, antigens, and trial results. Introduction. In the past decade, the substantial burden of respiratory syncytial virus (RSV) has received increasing recognition globally.
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