Guidelines for the use of cell lines in biomedical research
WEBAug 12, 2014 · Human and mouse feeder cell lines used to grow stem cells may also carry viruses and can present similar risks to those for continuous and finite cell lines (see Section 3.1.6).
Susceptibility to SARS-CoV-2 of Cell Lines and Substrates …
WEBFeb 24, 2021 · Almost all nonhuman primate cell lines were susceptible to icSARS-CoV-2-mNG infection except for CV-1 cells (Figure 1). In contrast, none of the tested human, mouse, mink, dog, or cat cell lines yielded fluorescent cells after infection.
SARS-CoV-2 vaccine ChAdOx1 nCoV-19 infection of human cell lines ...
WEBMar 15, 2021 · Almuqrin, A., Davidson, A.D., Williamson, M.K. et al. SARS-CoV-2 vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals low levels of viral backbone gene transcription alongside very high levels of SARS-CoV-2 S glycoprotein gene transcription.
Screening human cell lines for viral infections applying RNA-Seq …
WEBJan 10, 2019 · The development of free and publicly available interactive metagenomics analysis software and the availability of RNA-Seq, WES, and WGS data enabled us to screen cell lines for a multitude of viruses by screening of nucleotide sequences not mapping to the human genome.
Table 1 - Susceptibility to SARS-CoV-2 of Cell Lines and …
WEBTable 1. Overview of commercial cell lines used in study of susceptibility to SARS-CoV-2 of cell lines and substrates used to diagnose and isolate influenza and other viruses* *AdV, adenovirus; CMV, cytomegalovirus; HSV, herpes simplex virus; RhMK, rhesus monkey kidney; RSV, respiratory syncytial virus; VZV, varicella zoster virus. .
Detection of viral infection in cell lines using ViralCellDetector
WEBJul 21, 2023 · Currently, there are no established methods or tools available for detecting viral infections in cell lines. To address this challenge, we developed a tool called ViralCellDetector that detects viruses through mapping RNA-seq data to …
Transcriptomic profiling of SARS-CoV-2 infected human cell lines ...
WEBMar 19, 2021 · Article. Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy. Author links open overlay panel. Emanuel Wyler 1 9. , Kirstin Mösbauer 2 9. , Vedran Franke 1 9. , Asija Diag 1. , Lina Theresa Gottula 2. , Roberto Arsiè 1. , Filippos Klironomos 1 …
Quinine Inhibits Infection of Human Cell Lines with SARS-CoV-2
WEBApr 9, 2021 · Abstract. While vaccination campaigns are ongoing worldwide, there is still a tremendous medical need for efficient antivirals against SARS-CoV-2 infection.
Screening for 15 pathogenic viruses in human cell lines registered …
WEBMay 2, 2018 · Viruses in the other 23 cell lines and one EBV transformed cell line are derived from an in vivo infection, including five de novo identifications of EBV, B19V or HHV-7 carriers. Among them, 17 cell lines were established from patients diagnosed with virus-associated diseases.
Viral contamination in biologic manufacture and implications for ...
WEBApr 27, 2020 · 107 Citations. 342 Altmetric. Metrics. Abstract. Recombinant protein therapeutics, vaccines, and plasma products have a long record of safety. However, the use of cell culture to produce...
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